SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

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                                  SCHEDULE 13G
                                 (Rule 13d-102)

             INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT
           TO RULES 13d-1(b),(c) AND (d) AND AMENDMENTS THERETO FILED
                            PURSUANT TO RULE 13d-2(b)
                               (Amendment No. )(1)


                                 NuVasive, Inc.
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                                (Name of Issuer)


                          Common Stock, $.001 par value
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                         (Title of Class of Securities)


                                   670704 10 5
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                                 (CUSIP Number)


                                  May 12, 2004
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             (Date of Event Which Requires Filing of this Statement)

Check the appropriate box to designate the rule pursuant to which
this Schedule is filed:

         [ ] Rule 13d-1(b)

         [ ] Rule 13d-1(c)

         [X] Rule 13d-1(d)



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(1) The remainder of this cover page shall be filled out for a reporting
person's initial filing on this form with respect to the subject class of
securities, and for any subsequent amendment containing information which would
alter disclosures provided in a prior cover page. The information required on
the remainder of this cover page shall not be deemed to be "filed" for the
purpose of Section 18 of the Securities Exchange Act of 1934 or otherwise
subject to the liabilities of that section of the Act but shall be subject to
all other provisions of the Act.

CUSIP No. 670704 10 5 Page 2 of 7 Pages -------------------------------- 1. NAMES OF REPORTING PERSONS I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY) Johnson & Johnson 22-1024240 -------------------------------- 2. CHECK THE APPROPRIATE BOX IF (a) [ ] A MEMBER OF A GROUP (b) [ ] -------------------------------- 3. SEC USE ONLY -------------------------------- 4. CITIZENSHIP OR PLACE OF ORGANIZATION New Jersey -------------------------------- NUMBER OF 5. SOLE VOTING POWER SHARES BENEFICIALLY -0- OWNED BY EACH 6. SHARED VOTING POWER REPORTING PERSON WITH 1,491,132 shares of Common Stock 7. SOLE DISPOSITIVE POWER -0- 8. SHARED DISPOSITIVE POWER 1,491,132 shares of Common Stock -------------------------------- 9. AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON 1,491,132 shares of Common Stock -------------------------------- 10. CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES [ ] -------------------------------- 11. PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9) 6.25% -------------------------------- 12. TYPE OF REPORTING PERSON CO -------------------------------- -2-

CUSIP No. 670704 10 5 Page 3 of 7 Pages -------------------------------- 1. NAMES OF REPORTING PERSONS I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY) Johnson & Johnson Development Corporation 22-2007137 -------------------------------- 2. CHECK THE APPROPRIATE BOX IF (a) [ ] A MEMBER OF A GROUP (b) [ ] -------------------------------- 3. SEC USE ONLY -------------------------------- 4. CITIZENSHIP OR PLACE OF ORGANIZATION New Jersey -------------------------------- NUMBER OF 5. SOLE VOTING POWER SHARES BENEFICIALLY -0- OWNED BY EACH ---------------------------------------- REPORTING 6. SHARED VOTING POWER PERSON WITH 1,225,400 shares of Common Stock ---------------------------------------- 7. SOLE DISPOSITIVE POWER -0- ---------------------------------------- 8. SHARED DISPOSITIVE POWER 1,225,400 shares of Common Stock -------------------------------- 9. AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON 1,225,400 shares of Common Stock -------------------------------- 10. CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES [ ] -------------------------------- 11. PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9) 5.1% -------------------------------- 12. TYPE OF REPORTING PERSON CO -------------------------------- -3-

CUSIP No. 670704 10 5 Page 4 of 7 Pages -------------------------------- 1. NAMES OF REPORTING PERSONS I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY) Alza Corporation 77-0142070 -------------------------------- 2. CHECK THE APPROPRIATE BOX IF (a) [ ] A MEMBER OF A GROUP (b) [ ] -------------------------------- 3. SEC USE ONLY -------------------------------- 4. CITIZENSHIP OR PLACE OF ORGANIZATION Delaware -------------------------------- NUMBER OF 5. SOLE VOTING POWER SHARES BENEFICIALLY -0- OWNED BY EACH ---------------------------------------- REPORTING 6. SHARED VOTING POWER PERSON WITH 265,732 shares of Common Stock ---------------------------------------- 7. SOLE DISPOSITIVE POWER -0- ---------------------------------------- 8. SHARED DISPOSITIVE POWER 265,732 shares of Common Stock -------------------------------- 9. AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON 265,732 shares of Common Stock -------------------------------- 10. CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES [ ] -------------------------------- 11. PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9) 1.1% -------------------------------- 12. TYPE OF REPORTING PERSON CO -------------------------------- -4-

CUSIP No. 670704 10 5 Page 5 of 7 Pages Schedule 13G ------------ ITEM 1(a) - NAME OF ISSUER: NuVasive, Inc. ITEM 1(b) - ADDRESS OF ISSUER'S PRINCIPAL EXECUTIVE OFFICES: 10065 Old Grove Road San Diego, CA 92131 ITEM 2(a) - NAME OF PERSON FILING: This statement is being filed by Johnson & Johnson, a New Jersey corporation ("J&J"), Johnson & Johnson Development Corporation, a New Jersey corporation ("JJDC") and Alza Corporation, a Delaware corporation ("Alza"). JJDC and Alza are wholly-owned subsidiaries of J&J. The securities reported herein as being held by J&J, JJDC and Alza are directly beneficially owned by JJDC and Alza. J&J may be deemed to indirectly beneficially own the securities that are directly beneficially owned by JJDC and Alza. ITEM 2(b) - ADDRESS OF PRINCIPAL BUSINESS OFFICE: J&J and JJDC: One Johnson & Johnson Plaza, New Brunswick, NJ 08933 Alza: 1900 Charleston Road, Mountain View, CA 94309 ITEM 2(c) - CITIZENSHIP: J&J: New Jersey JJDC: New Jersey Alza: Delaware ITEM 2(d) - TITLE OF CLASS OF SECURITIES: Common Stock, $.001 par value per share ("Common Stock") ITEM 2(e) - CUSIP NUMBER: 670704 10 5 ITEM 3 - STATEMENTS FILED PURSUANT TO RULES 13D-1(B) OR 13D-2(B) OR (C): Not applicable. ITEM 4 - OWNERSHIP: (a) Amount Beneficially Owned: J&J: 1,491,132 shares of Common Stock JJDC: 1,225,400 shares of Common Stock Alza: 265,732 shares of Common Stock (b) Percent of Class: J&J: 6.25% -5-

CUSIP No. 670704 10 5 Page 6 of 7 Pages JJDC: 5.1% Alza: 1.1% (c) Number of shares as to which such person has: (i) sole power to vote or to direct the vote: -0- (ii) shared power to vote or to direct the vote: J&J: 1,491,132 shares of Common Stock JJDC: 1,225,400 shares of Common Stock Alza: 265,732 shares of Common Stock (iii) sole power to dispose or to direct the disposition of: -0- (iv) shared power to dispose or to direct the disposition of: J&J: 1,491,132 shares of Common Stock JJDC: 1,225,400 shares of Common Stock Alza: 265,732 shares of Common Stock ITEM 5 - OWNERSHIP OF FIVE PERCENT OR LESS OF A CLASS: Not applicable. ITEM 6 - OWNERSHIP OF MORE THAN FIVE PERCENT ON BEHALF OF ANOTHER PERSON: Not applicable. ITEM 7 - IDENTIFICATION AND CLASSIFICATION OF THE SUBSIDIARY WHICH ACQUIRED THE SECURITY BEING REPORTED ON BY THE PARENT COMPANY: Not applicable. ITEM 8 - IDENTIFICATION AND CLASSIFICATION OF MEMBERS OF THE GROUP: Not applicable. ITEM 9 - NOTICE OF DISSOLUTION OF GROUP: Not applicable. ITEM 10 - CERTIFICATION: Not applicable. -6-

CUSIP No. 670704 10 5 Page 7 of 7 Pages SIGNATURE After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct. JOHNSON & JOHNSON By /s/ MICHAEL H. ULLMANN -------------------------------- Name: Michael H. Ullmann Title: Secretary JOHNSON & JOHNSON DEVELOPMENT CORPORATION By /s/ MANISH YADAV -------------------------------- Name: Manish Yadav Title: Secretary ALZA CORPORATION By /s/ MICHELLE M. DAIGNEAULT -------------------------------- Name: Michelle M. Daigneault Title: Secretary Dated: February 1, 2005 -7-