NuVasive Investor Relations

NuVasive is a world leader in minimally invasive, procedurally-integrated spine solutions. From complex spinal deformity to degenerative spinal conditions, NuVasive is transforming spine surgery with innovative technologies designed to deliver reproducible and clinically proven surgical outcomes.

Press Release

NuVasive Announces Conference Call and Webcast Regarding Reimbursement

SAN DIEGO, Nov. 25 /PRNewswire-FirstCall/ -- NuVasive, Inc. (Nasdaq: NUVA), a medical device company focused on developing products for minimally disruptive surgical treatments for the spine, announced today that it will host a conference call on Monday, November 30, 2009, at 5:30 p.m. ET / 2:30 p.m. PT. The conference call will focus on current issues relative to reimbursement for the Company's products and will include comments from management followed by a short question and answer session. The dial-in numbers are 1-877-407-4018 for domestic callers and 1-201-689-8471 for international callers. A live webcast of the conference call will be available online from the investor relations page of the Company's corporate website at www.nuvasive.com.

As a reminder, management will be presenting at the 21st Annual Piper Jaffray Health Care Conference at the New York Palace in New York, New York, on Wednesday, December 2, 2009, at 10:00 a.m. ET. and at the J.P. Morgan SMid Cap Conference at the J.P. Morgan Conference Center in New York, New York, on Thursday, December 3, 2009, at 1:30 p.m. ET. A live webcast of both presentations will be available online from the investor relations page of the Company's corporate website at www.nuvasive.com.

After Monday's live webcast, the call will remain available on NuVasive's website, www.nuvasive.com, through December 30, 2009. In addition, a telephonic replay of the call will be available until December 14, 2009. The replay dial-in numbers are 1-877-660-6853 for domestic callers and 1-201-612-7415 for international callers. Please use account number 3055 and conference ID number 338644.

About NuVasive

NuVasive is a medical device company focused on the design, development, and marketing of products for the surgical treatment of spine disorders. The Company's product portfolio is focused primarily on the $4.6 billion U.S. spine implant market. Additionally, the Company has expanded into the $1.5 billion global biologics market, the $1.5 billion international market, and is developing products for the emerging motion preservation market.

NuVasive's principal product offering is based on its Maximum Access Surgery, or MAS® platform. The MAS platform combines four categories of products that collectively minimize soft tissue disruption during spine surgery with maximum visualization and safe, easy reproducibility for the surgeon: NeuroVision®, a proprietary software-driven nerve avoidance system; MaXcess®, a unique split-blade retractor system; a wide variety of specialized implants; and several biologic fusion enhancers. MAS significantly reduces surgery time and returns patients to activities of daily living much faster than conventional approaches. Having redefined spine surgery with the MAS platform's lateral approach, known as eXtreme Lateral Interbody Fusion, or XLIF®, NuVasive has built an entire spine franchise. With nearly 50 products today spanning lumbar, thoracic and cervical applications, the Company will continue to expand and evolve its offering predicated on its R&D focus and dedication to outstanding service levels supported by a culture of Absolute Responsiveness®.

NuVasive cautions you that statements included in this press release that are not a description of historical facts are forward-looking statements that involve risks, uncertainties, assumptions and other factors which, if they do not materialize or prove correct, could cause NuVasive's results to differ materially from historical results or those expressed or implied by such forward-looking statements. The potential risks and uncertainties that could cause actual growth and results to differ materially include, but are not limited to: the uncertain process of seeking regulatory approval or clearance for NuVasive's products or devices, including risks that such process could be significantly delayed; the risk that government or private payers may deny reimbursement to hospitals for use of the Company's products; the risk that NuVasive may be unsuccessful in its efforts to convince government or private payers to provide adequate reimbursement for its products; the possibility that the FDA may require significant changes to NuVasive's products or clinical studies; the risk that products may not perform as intended and may therefore not achieve commercial success; the risk that competitors may develop superior products or may have a greater market position enabling more successful commercialization; the risk that additional clinical data may call into question the benefits of NuVasive's products to patients, hospitals and surgeons; and other risks and uncertainties more fully described in NuVasive's press releases and periodic filings with the Securities and Exchange Commission. NuVasive's public filings with the Securities and Exchange Commission are available at www.sec.gov. NuVasive assumes no obligation to update any forward-looking statement to reflect events or circumstances arising after the date on which it was made.

Contact:                        Investors:
Michael J. LambertPatrick F. Williams
                                 Vice President, Finance & Investor
EVP & Chief Financial Officer    Relations
NuVasive, Inc.NuVasive, Inc.
858-909-1998                    858-638-5511
investorrelations@nuvasive.com  investorrelations@nuvasive.com

                                Media:
                                Jason RandoThe Ruth Group
                                646-536-7025
                                jrando@theruthgroup.com

SOURCE NuVasive, Inc.

Michael J. Lambert, EVP & Chief Financial Officer, +1-858-909-1998; Investors: Patrick F. Williams, Vice President, Finance & Investor Relations, +1-858-638-5511, both of NuVasive, Inc., investorrelations@nuvasive.com; Media: Jason Rando of The Ruth Group, +1-646-536-7025, or jrando@theruthgroup.com, for NuVasive, Inc.